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Question about contrave

My primary ia putting me on contrave for weight loss/depression. Its bupropion and naltrexone.

Wondering if anyone knows how this compares to a LDN regimen that others have seen help their crohns?


Hi Aideen, sorry that I didn't see this until now. I'm not an expert, so take this with a grain of salt, but the typical agreed-upon dosage amount for LDN is 4.5mg, once per day. I took a quick look at the Contrave website, and it looks like the naltrexone is an 8mg dose in an extended-release capsule format. That's certainly a lower dose than normal naltrexone (standard doses for generic naltrexone HCl are 50mg pills), but I'm not sure whether 8mg would have the same effects as traditional LDN.

My guess: I don't think that it will hurt anything, but I don't know that it will have a tangible effect on your Crohn's.

Hopefully someone else can chime in that has a little bit more knowledge on the subject.