I was on remicade years ago. I took myself off because of how much it cost. That was a big mistake. I had a flare and ended up having a resection. Several months after the resection they tried to put me back on the Remicade. By that time, my body had built up resistance to it. I had a lesion in my scalp which couldn't be treated with antibiotics. It had to be removed surgically. Ask your doctor if you have been off it too long. If not, go back on it. If you can't go back on it, ask your doctor about another biologic. Let us know how you are.