Hi there, I am 41 & my husband & I conceived our first child easily back in 2008, despite the fact that I'd had Crohn's related surgery in 2006, but at that time the Crohn's was undiagnosed. However, after problems through 2011 & 2012 and going onto Remicade since October 2012, my husband & I are struggling to conceive. We've been trying since May 2013 & have had all the tests: sperm, bloods, hysterosalpingogram & ultrasound & everything is ok which is hopeful. It's just sitting in the 'unexplained fertility' folder though! Our only other option is IVF. My concerns are this: Remicade suppresses the immune system & there are suggestions that taking it makes you weaker to fight anything & I mean anything that affects health. Therefore, do I want more meds in my system from IVF bearing in mind the risks that come with IVF drugs & the chances of Remicade possibly making me weaker to those risks if that makes sense? Any advice?....one nervous lady here! : )