Remicade

[Crohnsgrl]

Has anyone on remicade notice elevated lipids higher cholesterol triglycerides just wondering if it’s been noted to raise it thanks for any info

 

[my little penguin]

Changes in lipid profile during infliximab and corticosteroid treatment in rheumatoid arthritis - PubMed

Overall, no changes in serum lipid levels were observed after 48 weeks of infliximab treatment. The initial beneficial effects of infliximab on the lipid profile, by means of a reduction of disease activity, are attenuated by a concomitant decrease in prednisone dose.

pubmed.ncbi.nlm.nih.gov

Carbohydrate and Lipid Metabolism Following Infliximab Therapy in Pediatric Crohn's Disease - Pediatric Research

Improvements in insulin resistance after anti-TNF-α therapy have been reported in inflammatory conditions, although no changes were noted in adult patients with Crohn's disease. There is no information concerning insulin resistance and substrate metabolism in children with Crohn's disease after...

www.nature.com

Abstract
Patients with rheumatoid arthritis (RA) frequently display an atherogenic lipid profile which has been linked with inflammation. Tumor necrosis factor-alpha (TNF-alpha), a pivotal pro-inflammatory cytokine in RA may be involved in the development of the disturbed lipid metabolism. We investigated whether infliximab, an anti-TNF-alpha therapy, may modify the lipid profile. 56 consecutive RA patients were treated with infliximab (3 mg/kg at weeks 0, 2, 6, 14, 22, 30). Lipid profile and CRP were assayed at baseline and before infusion at weeks 6 and 30. Baseline values were compared with those in 56 healthy volunteers. At baseline, the concentrations of HDL-cholesterol were lower in RA patients than in the controls (1.3+/-0.4 vs. 1.5+/-0.2 mmol/L; p<0.01). The triglyceride concentrations (1.6+/-0.8 vs. 1.3+/-0.4 mmol/L, p<0.01), the ratio of total cholesterol/HDL-cholesterol (4.3+/-1.6 vs. 3.2+/-0.5, p<0.001) and LDL-cholesterol/HDL-cholesterol (2.6+/-1.2 vs. 1.7+/-0.5, p<0.001) were significantly higher in RA patients than in controls. After 6 weeks of infliximab therapy, the mean total cholesterol concentration increased by 25% (p<0.001), LDL-cholesterol by 24% (p<0.001) and HDL-cholesterol by 30% (p<0.001). The decrease in CRP levels to 30 week inversely correlated with the increase in HDL-cholesterol (r=-0.47, p=0.005). Infliximab administration is associated with important increases in cholesterol levels in all its forms but as no significant beneficial effect on the atherogenic ratio.

From

Effects of repeated infliximab therapy on serum lipid profile in patients with refractory rheumatoid arthritis | Request PDF

Request PDF | Effects of repeated infliximab therapy on serum lipid profile in patients with refractory rheumatoid arthritis | Patients with rheumatoid arthritis (RA) frequently display an atherogenic lipid profile which has been linked with inflammation. Tumor necrosis... | Find, read and cite...

www.researchgate.net

 

[Redfox99]

No , Im on the border of having high cholesterol but it runs in the family , I just eat well and exercise