I have a permanent colostomy and have severe diarrhea, so much so that everything I drink comes back out within 30 seconds to a minute.I am at my wits end over this.I am so thirsty all the time and recently have been craving grapefruit juice with a lot of salt and ice in it to drink.I have tried lomotil and imodium with no success and now my Dr. has called in something called Questran powder,it hasn't come in yet as the pharmacy had to order it, has anyone else had this problem or is familiar with questran?I have an appt. with my surgeon on the 12th about the progress of my gigantic open anal fistula that was found during the removal of my anus and rectum in Feb.This thing has so much drainage that I have to wear Depends and change several times a day.I don't know if this has anything to do with the diarrhea problem.I have had diarrhea for years because of Crohns, and had Anal cancer about 3 years ago.Chemo and Radiation did a lot of damage so that is the reason for the colostomy.I can't live like this forever,I either can't leave my house or I can't drink anything,its a no win situation.If anyone can provide some insight it would be greatly appreciated.