In April 2020 my 12 yo was diagnosed w/Crohns (he has been through testing and appointments since November '19), 3 days later his biopsy came back and they changed it to UC/undetermined. At the end of August he was hospitalized due to anemia and they did a pill cam test. They found ulcers all through the GI tract and on his Small Intestine. So, Crohns is the diagnosis again. They started him on Prednisone and Imuran with the hopes Imuran would work, would then introduce Entyvio shy away from Imuran and see if we could get away w/Entyvio on it's own due to minimal to no side effects and being gut specific. Unfortunately, 4 weeks into Imuran, his symptoms were worsening and his lipase was elevated. His body was not a fan of Imuran. So, here we are again in the hospital, he received another 2 units of blood and we will jumping on the Remicade train. Of course back in Apri when this medication was discussed, it was very overwhelming and scary. Our first reaction was heck no. After him battling this for 10 months now, researching and reading some messages in this forum, we actually feel way more comfy to make the jump and at this point it's hands up in the air, just do what you have to do to make him better. Yesterday he had a 102.2 temp, low BP, tacky/rapid pulse, low hemoglobin, elevated lipase, elevated white blood cells, low sodium, low potassium and honestly had never looked so bad. It was scary. He will also be taking methotrexate which also is a bit scary. Thank you to everyone that takes the time to post on forums like this it was very helpful for us and I'm sure others, it does make a difference. Also, I would love any type of feedback regarding experience with either drug.