Supplement EN helps sustain remission

[Patricia56]

http://www.biomedcentral.com/1471-230X/14/50/abstract

A retrospective study showing Maintenance treatment options for paediatric CD in the first year following diagnosis after induction of remission with EEN: supplemental enteral nutrition is better than nothing!

This study examined remission rates in children who used EEN to achieve remission and then either went on AZA or used EN as a supplement but did not use meds.

The remission rate at 1 year for the AZA group was 65%. The remission rate for the EN group was 60%. The remission rate for those who used nothing was 15%.

This is great info but I would express caution in generalizing the results as the numbers in the study were very small. The EN group was only 15 children and only 9 of those retained remission.

I have also posted the link in research articles.

 

[Tesscorm]

Wondering... in this study, and in others, is remission assumed to be biochemical remission or could they be referring to clinical remission only?

 

[Patricia56]

Probably clinical remission. The abstract didn't say what measure they used so it could even be the PCDAI which is not a very good measure of remission.

I didn't review the article just the abstract so you could look up the article and let us know.

 

[Tesscorm]

Just read it, they are using clinical remission. I find this term so misleading as 'clinical remission' is not really remission!! In my mind, while clinical remission is obviously a step in the right direction, using the word 'remission' (without further clarification) implies that you've reached the goal.

Let's just rewrite the textbooks and call it clinical recovery!

 

[imaboveitall]

V was in clinical remission for three years post-dx with just formula feeds. Inflammation was always present, though.

 

[Tesscorm]

Yes, same with Stephen... certainly not that I wanted S on drugs but, as I said above, between the term clinical remission and the fact that I was a newbie (ignorance is bliss ), S also had inflammation for two years while on maintenance EN only.