This is a general sort of question but since I started Stelara about 4 months ago thought I would ask here. I was on Remicade for about 4 years after going through a few years and little effectiveness from Budesonide. Even when the Dr would do colonoscopy and say there was little or no inflammation when Remicade was working I would get days of pain and other symptoms. Now, after a few months where felt better on Stelara I am having a rough few days after my last injection of pain, loose stools, and what I think is blood in stools. Wondering if even when a drug is effective for the most part if one can have small flares or days of discomfort. I tend to think that it will either work or not and I'll feel "normal" until it stops working completely. That didnt' seem to be the case with Remicade as I would go to the doc complaining of pain and colonoscopy and blood work would be great. Possibly the same going on here with Stelara that short term issues don't mean the drug isn't working or won't work as it gets more into my system. Curious what others experiences are with Crohn's symptoms and drug effectiveness. Thanks.