I had my blood work done and a colonoscopy done this week and everthing came back normal. So, i did it 15 years without medication through diet and exercise and i am going to do it again. According to my GI specialist my bowel was prestige no inflammation and no narrowing and very well. so i told him i wasn't going to take anymore medication and he said that is your decision to make! So i am making it i believe the medication made me worse instead of better. Anyway that is the scoop.