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A long time before I was diagnosed with Crohn's Disease ,I ate venison a couple of times and it didn't bother my stomach. Last night ,I had some and I was on the toilet four or five times. Why did I have trouble tolerating it last night?
I think the answer is in your message- pre CD you were fine, and post CD you were not.
Something about the venison I should think does not agree with your system now you have Crohn's disease.
Also it sounds like something you eat rarely so that could be another factor.
I have had to give up many foods since becoming sick. Some I give up totally but others I try again with after a little while when my confidence is back. Then I find out whether I can (or should) resume a favourite food and sometime's I can't.
In addition occasionally I can successfully build up a tolerance to something which bothered me in a large dose.