I was on Remicade several years ago and it worked great for me, until it stopped. I tried Humira, which didn't work great for me so after about a year and a half break my GI thought we should try Remi again. The first infusion was fine. They pre-medicated me with benadryl and steriods. After a week, I started having really bad joint pains. I didn't think it was the Remi, but rather just a reaction from all the inflamation I have. Second infusion yesterday did not go well. They pre-medicated again, which caused me to fall asleep. The nurse came in to take vitals and when I sat up she asked if I was ok and I shook my head no. I didn't know what was wrong but I knew something wasn't right. She walked out and within 3-5 seconds I couldn't breath, talk, started burning all over, turned bright red and thought I was dying. Luckily there was a guy in the room with me and he started screaming for help. They rushed in, cut off the line, gave my oxygyn, more steroids and benadryl. After I started breathing again, I started vomiting and having severe stomach cramping. This was honestly the scariest experience of my life. I really thought I was dying. I would never want to detere anyone from getting Remi, it worked wonders for me the first time. I did want to share my experience though. I am now onto Methotrexate and Cizma.