So I just started MTX on Saturday. I woke up this morning nauseous and with a killer headache. I popped a couple excedrin migraine. Then I got on here and read I'm not supposed to take aspirin with mtx, which is in excedrin. I know I can't take ibuprofen/aleve. What can I take for a headache? Acetaminophen? That's not aspirin, right? Should I call my doc and tell her I had aspirin? I didn't know I wasn't supposed to take it. :shifty: