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    Use of elemental diets in the 70s and early 80s.

    Wait, why are pro/prebiotics considered antigens?
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    Another JAK1 inhibitor fails clinical trials for crohn's disease.

    I just saw this announcement, not JAK1 related, but about Takedas completing the acquisition of Nimbus: https://www.nimbustx.com/2023/02/08/nimbus-therapeutics-announces-closing-of-takedas-acquisition-of-tyk2-subsidiary/ What do you think about this trial for psoriasis? I imagine if this works...
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    Use of elemental diets in the 70s and early 80s.

    Modulen is available for the US market. I purchased mine here: https://www.nestlenutritionstore.com/modulenr.html
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    Use of elemental diets in the 70s and early 80s.

    I don't think I heard of any recall for Modulen and Neocate. Might be better quality control.
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    Use of elemental diets in the 70s and early 80s.

    I've heard a concern that gets brought up often and that's the formula recall that tends to go around from brand to brand. I think a while back it was Ensure and then the famous Kate Farms got hit too.
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    Use of elemental diets in the 70s and early 80s.

    I had just made a comment on a thread lamenting the fact that we might be facing the cure ie EEN (at least for now & the only non-pharmaceutical option) that is in front of us all this time but are not able to embrace it. So when we say we will do anything for a cure we might need to make that...
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    High Calprotectin - On Remicade

    Skyrizi is our doctor's preferred choice too (over Stelara) if the insurance will approve. Best luck. (y)
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    Use of elemental diets in the 70s and early 80s.

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    Skin microbiota signature distinguishes IBD patients and reflects skin adverse events during anti-TNF therapy

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872723/
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    Crohn's disease happens in clusters, and no one knows why.

    Yeah a lot of people are so excited about the trial result release date. I dont know why I am not holding my breath? There has been no update and not even a preview of what's to come. I tend to interpret no communication to be things are not going well. I hope I am wrong.
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    Overrepresentation of Enterobacteriaceae and Escherichia coli is the major gut microbiome signature in Crohn’s disease and ulcerative coli

    I am only aware of one such trial at Mt Sinai: http://www.intralytix.com/index.php?page=news&id=90 Active recruiting: Dr. Hirten's email: [email protected] He is super accessible. My son is too young to participate but perhaps you can reach out.
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    Overrepresentation of Enterobacteriaceae and Escherichia coli is the major gut microbiome signature in Crohn’s disease and ulcerative coli

    I mean we can use the case of people who slowly add solids back into the diet once they achieve full remission using EEN. The inflammation comes back and it's very hard for me to think that solids bring on the problem especially if the gut is healed fully. However solid foods are an event for...
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    Overrepresentation of Enterobacteriaceae and Escherichia coli is the major gut microbiome signature in Crohn’s disease and ulcerative coli

    OK, now I am in a knot. So if a person on medication achieves mucosal healing, are we saying that 1) the pathogen is successfully eliminated *and* 2) the immune system on overdrive is calmed to a normal level? I don't think so, right? It seems to me that the medication only does 2) and when the...
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    Overrepresentation of Enterobacteriaceae and Escherichia coli is the major gut microbiome signature in Crohn’s disease and ulcerative coli

    Obviously Moderna wants to have a play in this so they brought Dr. Jeffrey out of academics and made her the head of this new division. Her findings esp the second part of the video are impressive. She was certain, backed up by all the patient data at her hospital and proposed to solve it using...
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    Dr. Rosh - Pediatric IBD Treatment Beyond Anti-TNFs

    He mentioned "antibiotics cocktail" which is very very interesting.
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    Use of elemental diets in the 70s and early 80s.

    @kiny why was 8-10g of nitrogen given to patients daily in addition the drinks?
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    Dr. Rosh - Pediatric IBD Treatment Beyond Anti-TNFs

    https://naspghan.buzzsprout.com/581062/12111901-joel-rosh-pediatric-ibd-treatment-beyond-anti-tnfs
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    Sustained Diet-Induced Remission in Pediatric Crohn’s Disease Is Associated With Kynurenine and Serotonin Pathways

    How about bone broth? There is so much of goodness if you just cook it for a long time.
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    Sustained Diet-Induced Remission in Pediatric Crohn’s Disease Is Associated With Kynurenine and Serotonin Pathways

    I really like these two articles from Ray Peat on serotonin: 1) http://raypeat.com/articles/articles/serotonin-disease-aging-inflammation.shtml 2) http://raypeat.com/articles/aging/tryptophan-serotonin-aging.shtml He offers some diet advice too: In the traditional diet, rather than just eating...
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    Overrepresentation of Enterobacteriaceae and Escherichia coli is the major gut microbiome signature in Crohn’s disease and ulcerative coli

    Phage production is blocked in the adherent-invasive Escherichia coli LF82 upon macrophage infection Author summary Adherent-invasive Escherichia coli (AIEC) strains are frequently recovered from stools of patients with dysbiotic microbiota. They have remarkable properties of adherence to the...
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