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Crohn's Disease Forum

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  1. Crohn2357

    Anti-MAP Therapy Support Group

    Expert Rev Clin Immunol. 2011 Nov;7(6):751-60. doi: 10.1586/eci.11.43. Primary treatment of Crohn's disease: combined antibiotics taking center stage. Chamberlin W1, Borody TJ, Campbell J. Author information Abstract Although controversial, the use of properly chosen antibiotics in Crohn's...
  2. Crohn2357

    QBECO-SSI Clinical Trial

    [URL unfurl=true]https://www.healingwell.com/community/default.aspx?f=17&m=4087960&r=x[/URL] [URL unfurl=true]https://www.healingwell.com/community/default.aspx?f=38&m=4087962&g[/URL]
  3. Crohn2357

    Anti-MAP Therapy Support Group

    https://www.redhillbio.com/RedHill/Templates/showpage.asp?DBID=1&LNGID=1&TMID=178&FID=1395&PID=0&IID=12218
  4. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    I don’t take those that I have mentioned as the cause of Crohn’s; but I take them as solid risk factors for flare-ups, at the very least. There’s no sure way to get into remission with Crohn’s, but there are sure ways a Crohn’s patient can fall out of remission, and all of those ways share at...
  5. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    That’s what I asked you in the first place: I think we might had a misunderstanding then. But, regarding your question (“Why would they be more likely to be infected”), the rate of exposure would probably be same or very similar for both groups, but the patients on the immunosuppressants...
  6. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    I think getting more and better research on the histological changes in Crohn’s patients could provide great insights on the questions surrounding why flares occur, also make people question the current conceptions of remission, flare-ups, aetiology, pathogenesis, disease activity, prognosis...
  7. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    That’s why I am saying that the conclusion inferred from your propositions lead to a contradiction (with the statistical fact). If reinfection with the foodborne infections might explain the flare ups, and the CD patients who are on immunosuppressants are more likely to get a reinfection with...
  8. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    What I am saying is, if “getting reinfected with foodborne infections” might be an explanation for flaring, and being on immunosuppressants increase the likelihood of getting reinfected with foodborne infections, then wouldn’t people who use immunosuppressants be more likely to relapse than...
  9. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    kiny, I have been thinking about your proposal that flare-ups might be caused by re-infections with the suspected bacteria; if that was the case, wouldn’t people who use immunosuppressants (especially the combination therapies) flare-up more frequently than those who don’t, since they would be...
  10. Crohn2357

    Higher dose Entyvio

    Why do you think that, could you share?
  11. Crohn2357

    Anti-MAP Therapy Support Group

    https://humanpara.org/the-map-gap-newsletter-july-2019/
  12. Crohn2357

    Anti-MAP Therapy Support Group

    https://humanpara.org/clofazimine-practical-considerations-for-patients/
  13. Crohn2357

    Anti-MAP Therapy Support Group

    https://mailchi.mp/crohnsmapvaccine/introducing-world-map-day-and-the-crohns-map-vaccine-cured-not-managed-shop-1740145?e=2f7cd0cabe
  14. Crohn2357

    Ingredients in Biologics

    Here’s info on humira: https://www.rxabbvie.com/pdf/humira_medguide.pdf
  15. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    kiny, what is your opinion of Crohn’s disease that mostly or only manifests itself in the colon and anus, with minimal or no small intestinal involvement?
  16. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    Source (if anyone wants to read): Jostins, Luke et al. “Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.” Nature vol. 491,7422 (2012): 119-24. doi:10.1038/nature11582
  17. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    I have tried to raise awareness about Qu Biologics’ vaccine trial for Crohn’s by creating and updating these two threads in HealingWell’s CD and UC forums. https://www.healingwell.com/community/default.aspx?f=17&m=4087960&r=x https://www.healingwell.com/community/default.aspx?f=38&m=4087962&g...
  18. Crohn2357

    Remicade anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases

    Yeah, I got your point, but I think making a distinction between clinical trials - institutionally backed medical treatments and self experimentation is necessary here. I actually find the editor’s note and the fact that this journal decided to publish this article quite good. Sometimes those...
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