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Crohn's Disease Forum

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  1. M

    FECAL TRANSPLANTS: A Guide

    I guess I have a question I am not sure about. People get sick with a coliform infection from swimming pools, and sewage leaks into the ocean. They are always checking coliform levels. So if you eat pure poo, many/none perhaps do not get sick, so what is going on. We also know that some with UC...
  2. M

    FECAL TRANSPLANTS: A Guide

    WB As far as I know the small intestine is not sterile, has some bacteria of course not the amounts in the colon. With crohns,dysbiotic bacteria at early onset, with higher than normal counts. As I said above part of the problem is not flushing the bacteria from the crypts with thin expanded...
  3. M

    FECAL TRANSPLANTS: A Guide

    Since you are discussing poop pills,here is some info. Another side of this is that opposed to rectal infusion, what if oral tolerance is a mechanism that also induces remission. Anyhow drinking poo also might have some additional danger,such as aspiration into the lungs, where pills seem...
  4. M

    Crohns treatement meta analysis

    About 5 minutes old. Old Mike http://medicalxpress.com/news/2015-01-meta-analysis-tx-remission-crohn.html
  5. M

    MAP Vaccine Ready for Human Trials - Could be Used for Crohn's

    Well if MAP acts the same as TB then really difficult to get rid of. Hot off the press,zombie state. Old Mike http://medicalxpress.com/news/2015-01-zombie-bacteria-tuberculosis.html
  6. M

    Etiology of inflammatory bowel disease: A unified hypothesis

    Read these two again. http://www.ncbi.nlm.nih.gov/pubmed/8358131 http://www.ncbi.nlm.nih.gov/pubmed/17551835 It now occurs to me that if UC people can be put into remission just with the camostat or BBI,there are implications. Excess protease can come from digestive enzymes that are not...
  7. M

    Emerging Leadership Lecture: Inflammatory Bowel Disease in Asia: Emergence of a "Western Disease"

    korea They first discovered MAP in their herds in 1967,with a possible long incubation period from infection to IBD. It would be interesting to find other countries with a known MAP timeline and IBD incidence. Oh and by the way I spent a year in Korea 1971-1972,UC 1980, but I moved to my new...
  8. M

    FECAL TRANSPLANTS: A Guide

    By drinking poo there is a possibility that one reason it works is induction of oral immune tolerance to the bacteria, which may be lost in IBD. Loss of tolerance is an old IBD theory. Old Mike
  9. M

    Is grey hair related to Crohn's disease?

    Here is the root of the problem, you are being oxidized,and if the hair is actually white, I might guess there is a worse problem. Old Mike http://medicalxpress.com/news/2013-05-gray-hair-vitiligo-reversed-root.html
  10. M

    Perhaps our diet is just too good!!!

    Curiouser and curiouser. Brand new info. Seems juice and pulp have ten times more antioxidant capacity than believed. If you follow this thread too much antioxidant capacity impairs bacterial killing. Old Mike...
  11. M

    What's your theory on how you got Crohn's Disease?

    These may be of interest to some in this thread. Old Mike http://www.ijidonline.com/article/S1201-9712(14)01434-9/fulltext#tblfn0025 http://www.pulsus.com/cddw2010/abs/114.htm http://www.ncbi.nlm.nih.gov/pubmed/18070971 Thiopurine drugs azathioprine and 6-mercaptopurine inhibit Mycobacterium...
  12. M

    Research into MAP as the cause of Crohn's

    Here is an old 1991 paper. Old Mike http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC2399081&blobtype=pdf
  13. M

    Emulsifiers Detergents and IBD

    I was still am a big proponent of detergents causing gut problems. But went on a low detergent/low food emulsifier lifestyle for 3 months, but it did nothing for my UC. With crohns the mucus is too thick,and there is a bicarbonate transport problem in the small intestine,where bicarbonate ion...
  14. M

    TB Cure Maybe Responsible for Spontaneous remissions

    You might find this of interest. I also have other info that Remicade also controls MAP. Old Mike http://www.sciencedirect.com/science...01971214014349
  15. M

    UC Chronicity and biofilms

    Not talking about a biofilm on the outer mucus or in the outer mucus. This is a adherent biofilm that is attached to the mucosa, in the pictures. Simply replacing one mucosal biofilm with a new one from FTM will not work IMO. The biofilm has to go somehow,the mucus barrier needs to regenerate...
  16. M

    UC Chronicity and biofilms

    Nothing specific,but believe it to be a good idea, along with colon washout/lavage. As you see with the antibiotics the biofilm is still there, and if they are stopped there is a large rebound of bacteria in the biofilm. I am also starting to believe that FMT is not the ultimate probiotic, what...
  17. M

    UC Chronicity and biofilms

    Can anyone see a connection here. Bacteria and there biofilms should not physically touch our colon mucosa. Why no medical cure. The medical community are not targeting the cause. What's the cause. Persistent biofilm on the mucosa. Not saying this is the initial cause, but why there is no...
  18. M

    UC Why no medical cure

    This might also apply to crohn's, don't know. When the doc's say AIEC they really mean biofilm. Since this is a crohn's centric forum, will add this. http://www.ncbi.nlm.nih.gov/pubmed/23104802 http://www.biomedcentral.com/1471-2180/9/202 For me this has all come together in the last few days...
  19. M

    Perhaps our diet is just too good!!!

    See the internet brain is now sending me down a slightly different search path. Now searching exogenous antioxidants stool. Here is the first one I ran across. Conclusion: "So, antioxidant exacerbated B. hominis intensity but it decreased the pathological changes." I say dual result, oxidative...
  20. M

    Perhaps our diet is just too good!!!

    No question about it Kiny. But my point might be that in most people, ones without IBD, was the immune system able to kill off the AIEC invasion. If not, why not. Are all the exogenous antioxidants protecting bacteria from a rapid and deadly to them,immune response. Of course this also begs...
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