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Crohn's Disease Forum

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  1. M

    UCF researchers closing in on cure for Crohn's disease

    Kiny: you of course make some good points. I have UC . Quite smoking 1977,UC 1980,but 1979 moved into our new house which I still live in. 1/4 mile from working dairy farm,drank their milk,breath the cow dung dust. We also have a slaughter house about 4 miles away,they drive cattle/pig trucks...
  2. M

    UCF researchers closing in on cure for Crohn's disease

    This paper makes a lot of good points that MAP is the cause of both diseases. Old Mike http://www.gutpathogens.com/content/2/1/21
  3. M

    Plantain and Broccoli May Inhibit Crohn's Relapse, Polysorbate 80 May Increase Risks

    Polysorbate 60/80 a subject dear to my heart as well as all food emulsifiers as well as lecithin. Peg 6/12 in toothpaste,CMC,gums ect. We also have dishwashing detergents, clothes washing detergents,shampoo and what ever else contains detergents that we can ingest or absorb through the...
  4. M

    Etiology of inflammatory bowel disease: A unified hypothesis

    Xiaofa: Yes I have read those studies. They were used in bulk. I am worried about the following in food and applied to vegetables, polysorbate which is a PEG ester of sorbitan,peg-12,peg-8,both in toothpaste,PEG itself applied to vegetables. Once the polysorbate is digested it should free the...
  5. M

    Etiology of inflammatory bowel disease: A unified hypothesis

    Xiaofa: As you can see from the Pollen paper now that you have read it,that the mucus is first degraded by protease,then the pollen can penetrate the mucus barrier once this happens the immune system is then activated. Whether the weakened mucus barrier in the gut is due to active digestive...
  6. M

    Etiology of inflammatory bowel disease: A unified hypothesis

    Thank you Xiaofa: Interesting info. You might find this paper also very interesting. I believe that this is the same basic mechanism for UC, but in UC perhaps many different agents may accomplish the same end result. Old Mike link
  7. M

    Just found a mucus breacher in the diet

    I keep saying that PEG/polyethylene glycol in foods,ie polysorbate 60/80,PEG-12/8 in toothpaste might be a problem. They use straight PEG as a wax on veggies such as cukes,so must peel or buy at a farmers market where they probably are not coated. 'Here is more proof,brand new work, they are...
  8. M

    Just found a mucus breacher in the diet

    I have got a mucus breacher in the diet. PEG polyethylene glycol,cant find it is used in too many foods but energy drinks,gum,as a coating for fruits and veggies,also for colon prep and Miralax. Migration from food packaging to food. Better also check your toothpaste. Why does not Miralax...
  9. M

    A wild guess that baking soda might help Crohn's

    It is my understanding that in Crohn's disease the mucus is thicker than normal. From this paper ion transporters control the viscosity/expansion of the mucus in the small intestine. It seems the way the mucus is supposed to work in the small intestine is to volume expand and flush the bacteria...
  10. M

    Etiology of inflammatory bowel disease: A unified hypothesis

    Here is an older paper on mucus and protease in the colon,not sure if it has been referenced yet. It is cached so it does not format quite right. Old Mike Link
  11. M

    FECAL TRANSPLANTS: A Guide

    Here is some new info as to what is going on with the gut bugs after FT for uc. Old Mike http://www.ncbi.nlm.nih.gov/pubmed/24060759
  12. M

    Potential Crohn's treatment starts clinical trial

    FYI: Hot off the press. Old Mike http://medicalxpress.com/news/2013-09-potential-crohn-treatment-clinical-trial.html
  13. M

    Microbiota of De-Novo Pediatric IBD: Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative

    This seems to put a different perspective on IBD, no dsybiosis in early onset child colitis,that have not had meds. Crohn's a different story. WOW, might have to start back at square one,or or it is weak mucus due to perhaps proteolytic activity or something else. They pretty much say that...
  14. M

    Defective sugar perhaps root cause of colitis,The chicken or the egg perhaps solved

    Don't want you to miss this one. What has gone wrong is the question. How to fix is perhaps the bigger question. Will continue to work on it. Tie this in with they are not finding dysbiosis in early onset IBD in children which have not been medicated. It all begins to make more sense...
  15. M

    Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis.

    I have added some new material to my first post,makes a more complete story. The ecoli is just not supposed to be there in high numbers,plus what ever other nasty bacteria that might act the same. Old Mike
  16. M

    Etiology of inflammatory bowel disease: A unified hypothesis

    Here is the problem,as far as a bacteroides as a probiotic. Is FT the only solution,or can we somehow regrow our own. http://www.drmyhill.co.uk/wiki/Probiotics_-_we_should_all_be_taking_these_all_the_time_and_double_the_dose_following_antibiotics_and_gastroenteritis somewhat better article...
  17. M

    Etiology of inflammatory bowel disease: A unified hypothesis

    Really good find Wildbill. So good it might complete the circle. Here is another example for UC,same thing lowered bacteroides http://www.ncbi.nlm.nih.gov/pubmed/21073731 You might want to look at this thread I have on oxygen in the colon how it might relate to this,and perhaps provide an...
  18. M

    Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis.

    Hopefully I will get it close someday. Based on Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis. The key point I believe is that facultative anaerobes should not be present in any kind of high amounts. Seems like this is tying together. Inflammation, generates more oxygen in...
  19. M

    Larry Smarr

    Once you loose bacterial diversity it would seem to me that this is part of the mechanism driving continued inflammation. Old Mike http://www.ncbi.nlm.nih.gov/pubmed/21937990
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