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Hi Guys, I had a flexi- sigmoidoscopy at week 8 which showed some improvement. Doctors are thinking I may be on a lower dose of the drug. I am still experiencing all the symptoms and stool frequency is the same so I do qualify for entering the open label part of the study at week 12. Could...

Hi Kerdan, Nice to hear from you! Im sorry it didn't work out, i dont feel any better and im going into the 8th week sigmoidoscopy on Tuesday. So you went onto the open label for how long? And with no results? The mechanism of action is the same as Vedolizumab isnt it? People have had...

Hey guys, I have UC and am currently on the AMG 181 trial. Currently in week 7. I have had no improvement so far. Hoping this is to be my saviour as no other treatment has worked. Has anyone had good results with this post 8-12 weeks?