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Latest research is that combo meds help reduce likelihood of antibodies to remicade with mtx now the safer choice instead of [wiki2="6-Mercaptopurine"]6mp[/wiki2], so it's probably worth the side effects/risks. My son's doc wants him on mtx combo with Humira, but he's doing really well with Humira as monotherapy and the literature is mixed for that combo and for how long to overlap. He did do a year combo with 6mp to push him into [wiki2="Remission"]remission[/wiki2] already though.
