Antibacterial Activities of Naturally-Occurring Compounds against Mycobacterium avium

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http://crohn.ie/antibacterial-activ...obacterium-avium-subspecies-paratuberculosis/


The most effective compound was trans-cinnamaldehyde with a minimum inhibitory concentration (MIC) of 25.9 microg/ml, then cinnamon oil (26.2 microg/ml), oregano (68.2 microg/ml), carvacrol (72.2 microg/ml), 2,5-dihydroxybenzaldehyde (74 microg/ml), and 2- hydroxy-5-methoxybenzaldehyde (90.4 microg/ml). With the exception of carvacrol, a phenolic compound, three of the four most active compounds are aldehydes, suggesting that the structure of the phenolic group or aldehyde group may be important to the antibacterial activity.
 

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