Yes. I now have constant " black tongue" is what they call chronic thrush. It is terribly hard to treat if at all. Since budesonide is a " milder" sterod it does decrease our immune system, thus thrush! Ugh...it is somewhat embarrassing when speaking, so i take every precaution to minimize it. Good luck Warge, nystatin swish n swallow does help some since if its in the mouth it works its way down your throat. - hugs-