Chili peppers for a healthy gut: Spicy chemical may inhibit gut tumors

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Chili peppers for a healthy gut: Spicy chemical may inhibit gut tumors

The researchers fed capsaicin to mice genetically prone to developing multiple tumors in the gastrointestinal tract. The treatment resulted in a reduced tumor burden and extended the lifespans of the mice by more than 30 percent. The treatment was even more effective when combined with celecoxib, a COX-2 non-steroidal anti-inflammatory drug already approved for treating some forms of arthritis and pain.
"Our data suggest that individuals at high risk of developing recurrent intestinal tumors may benefit from chronic TRPV1 activation," said Raz. "We have provided proof-of-principle."

http://www.sciencedaily.com/releases/2014/08/140801213339.htm