The plan hasn't been to keep me on this drug for so long , but it seems to be the only thing that helps relieve my crohns symptoms . I have been the one who gets the negative side effects from the maintance drugs , ie ; methotrexate elevated my liver enzymes to high , humira gave me rhumatoid arthritis and drug induced lupus , Imuran gave me pancreatitis , and cimzia didn't seem to do anything so that ended with my second surgery . As for side effects of the steroid nothing noticable other than what the bone density test showed . Which was I have osteopenia . So now I take calcium, with fingers crossed . I don't like being on steroids , but hey right now things are fairly normal for me . I am back to work after being off for a year . Anyway I hope this helps you .