Eosinophil in duodenum and IBD development

[my little penguin]

from:

http://www.google.com/url?sa=t&rct=...SqNpWwTkXRGgNCjkNINnF1A&bvm=bv.52164340,d.aWM

Our data suggest that most children undergoing upper endoscopy for evaluation of GI
symptoms who have duodenal esosinophilic infiltrates have allergic history or symptoms.
The finding of a high prevalence (68%) of eosinophilic infiltrates at some GI site or specific to
the duodenum (37%) in this large sample size is noteworthy, but we did not identify
symptoms specific to children with DEI. Of importance, a small number (5%) of children with
DEI developed inflammatory bowel disease within three years.

After 12-36 months, a significant percentage of patients were still
symptomatic (failure to thrive: 57%, nausea: 55%, and abdominal pain: 44%) and 40% were
still on medications to control their symptoms. This indicates chronicity and the treatment
used was not effective. It was important to know that fourteen (5.6%) of children with DEI
developed IBD after only 12-36 months. Whether DEI is a predictor of pediatric IBD remains
to be proven.

:voodoo::voodoo::voodoo:

 

[killcolitis]

I came across this a while ago. My daughter did have duodenal eos at diagnosis and then some inflammation there later. She has a UC diagnosis.
Do you think it's allergy mediated?