Extreme Nausea

[Polaris]

I've been on 6mp for 2 weeks at 50mg. Per my GI I increased the dose to 100mg last night, and since then have been extremely nauseated, and vomiting last night. This is by far the worst nausea I've ever had, and the longest lasting. Zofran hasn't worked at all.

Did any of you experience this? It doesn't seem like a normal side effect to me (at this severity) and I'm hesitant to continue with the med. I have a note in to my doctor about what's going on of course, but just wanted your opinions/experience.

 

[nogutsnoglory]

Well it's a big jump and I felt awful going from 50 to 75 on 6mp years back. Maybe it's not the right dose or you need to go up more gradually.

 

[Polaris]

Well it's a big jump and I felt awful going from 50 to 75 on 6mp years back. Maybe it's not the right dose or you need to go up more gradually.

I think that might be the cause, too. My GI wants me to stay at 50mg and if it's not effective we'll move to another med, probably methotrexate I'm guessing.

 

[DJW]

Have you tried breaking the dose up through the day?

 

[Polaris]

Have you tried breaking the dose up through the day?

I haven't, but I will try that. I started with taking it at night because I read so many people were experiencing nausea initially, and this way could just sleep through it. Not in my case ha.

 

[DJW]

Thats too bad. I take it at night because I get sleepy.
Although that's not the case tonight.

 

[It takes Guts]

I started on 50mg for two weeks then took 100mg on alternate days, gradually building up to 100mg by week four. I was also on prednisone. As I came off the prednisone I started to experience extreme nausea. The smell of my usual soap, fabric conditioner,my own (clean!) body - all made me feel sick. I was also sleep fourteen plus hours a day. My crohns was vengeful! Finally someone suggested ginger biscuits. These helped combat the sick feeling.

I reported this all to my IBD nurse and after another blood test they realised the dose of 100mg was too high. I weigh 51kg. I was told to go down to 75- on practise I went down to 50 because I just wasnt functioning. After two weeks I upoed it to 75mg by taking 25mg with lunch and 50mg in the evening. Aside from a few blips I'm feeling better I think!certainly the nausea is give and the fatigue has lessened.

Hope this helps -apologies of it's too detailed. It's my first post.

Please report back his you feel. I want to know how people on same meds at same time get on.