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Does anyone out there do an injection a week? If so, do you have any suggestions, advice, good or bad things to say? Thanks.
Humira Once a Week?
- Thread starter SugarberryGA
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Help Support Crohn's Disease Forum:
For two years I was once every other week, worked very good until the symptoms started coming back. The dose was increased to once a week, made a little difference and then it started to fail too.
Now I am on Entyvio, six infusions with little progress.
May try Stelara off label use next.
Now I am on Entyvio, six infusions with little progress.
May try Stelara off label use next.
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Thanks, Fernando. I hope the Entyvio eventually works for you. May I ask what your Crohn's symptoms are? I've been having more and more abdominal pain over the past year or so. Before the Humira, fatigue was a biggie for me.
Have crohns for 45 years, I can write a book on the symptoms, for brevity I will summarize by decades:
1970-1980 - Severe diarrheah, bloating, malnutrition, loss of weight
1980-1990 - Fevers from abscesses, Crohns travels to colon, rectum, developed rectum abscess from so much diarrheah
1990-2000 - Strictures forming leading to bowel obstructions, severe pain, developed fistulas from the pressure on the instestines, one of them life threatening, massive bowel resection (5 feet), the secum in the colon 18 inches is removed.
2000-2015 - Travels to anus, bad case of perianal crohns - severe itching and ulcers in the rectum and anus. The irony is this: Crohns keeps traveling, traveling down the intestines, once it got to the anus it is pissed - it has nowhere else to go so it swirls around there, it is very very mad...More obstructions, vomiting which is a classical sign of obstruction (about 5-8 obstructions a year which led to hospital visits).
Now 5 years after the resection I developed an obstruction on the anastomosis (the point of resection) which happens a lot. Delaying the next surgery because I have less and less intestine left after each surgery, besides the anastomosis usually where the next surgery will happen. I am not vomiting yet nor do I have pain, once that starts I will have to have surgery because you run the risk of perforation.
I will say that if I had another ten feet beyond the anus Crohns will find its way there too !
In 2010 another bowel resection, removed 4 feet from the ileum. Still bloated, diarrheah managed somewhat - 6 times a day.
Until 1970-2005 was taking all the non-effective drugs: Azulfidine, Asacol, Pentasa. Some relief from Prednisone.
2009 - Started on Humira worked well for two years, now on Entyvio - not going well. May try Stelara.
1970-1980 - Severe diarrheah, bloating, malnutrition, loss of weight
1980-1990 - Fevers from abscesses, Crohns travels to colon, rectum, developed rectum abscess from so much diarrheah
1990-2000 - Strictures forming leading to bowel obstructions, severe pain, developed fistulas from the pressure on the instestines, one of them life threatening, massive bowel resection (5 feet), the secum in the colon 18 inches is removed.
2000-2015 - Travels to anus, bad case of perianal crohns - severe itching and ulcers in the rectum and anus. The irony is this: Crohns keeps traveling, traveling down the intestines, once it got to the anus it is pissed - it has nowhere else to go so it swirls around there, it is very very mad...More obstructions, vomiting which is a classical sign of obstruction (about 5-8 obstructions a year which led to hospital visits).
Now 5 years after the resection I developed an obstruction on the anastomosis (the point of resection) which happens a lot. Delaying the next surgery because I have less and less intestine left after each surgery, besides the anastomosis usually where the next surgery will happen. I am not vomiting yet nor do I have pain, once that starts I will have to have surgery because you run the risk of perforation.
I will say that if I had another ten feet beyond the anus Crohns will find its way there too !
In 2010 another bowel resection, removed 4 feet from the ileum. Still bloated, diarrheah managed somewhat - 6 times a day.
Until 1970-2005 was taking all the non-effective drugs: Azulfidine, Asacol, Pentasa. Some relief from Prednisone.
2009 - Started on Humira worked well for two years, now on Entyvio - not going well. May try Stelara.
Last edited:
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DS just started taking humira once a week
Had been in humira every two weeks for year
Then every 10 days for a year plus mtx
And now once a week plus mtx and crohns exclusive diet with partial enteral nutrition
Symptoms extreme constipation , rectal prolapse , abdominal pain , lack of appetite recital bleeding , mouth ulcers , arthritis and vasculitis
He was dx 4 years ago at age 7
Had been in humira every two weeks for year
Then every 10 days for a year plus mtx
And now once a week plus mtx and crohns exclusive diet with partial enteral nutrition
Symptoms extreme constipation , rectal prolapse , abdominal pain , lack of appetite recital bleeding , mouth ulcers , arthritis and vasculitis
He was dx 4 years ago at age 7
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SHIT!!! That scares me and I thought I've been through a lot. Wonder what's in store for me next
I have not mentioned the diminishing quality of life in these 4 decades, I did not want to depress the readers on what happens in the later stages of Crohns. Like having to wear diapers 7 x 24.
If you really want to know so you can be prepared, email me at [email protected]. On the other hand some of the things that are happening to me may never happen to you so you may not want to receive future predictions that will worry you unnecessarily.
On the good news front I am not wearing a colostomy bag, still have 60% of my colon left. There are some horrors awaiting there that I don't think I will ever be prepared to face.
My goal in participating in this forum is to give HELPFUL advice as to what to do, these public posts will remain that way !
If you really want to know so you can be prepared, email me at [email protected]. On the other hand some of the things that are happening to me may never happen to you so you may not want to receive future predictions that will worry you unnecessarily.
On the good news front I am not wearing a colostomy bag, still have 60% of my colon left. There are some horrors awaiting there that I don't think I will ever be prepared to face.
My goal in participating in this forum is to give HELPFUL advice as to what to do, these public posts will remain that way !
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- Sep 30, 2011
- Messages
- 110
Thanks, everyone. As for wearing diapers, I've sort of expected that might happen. I never leave home w/o wearing protection and carry extra pads with me in case there's an accident. Don't you just HATE Crohn's? I know I do. I try to keep a positive attitude, but it's not always easy. At least I'm 54 and have never had surgery, so things are all bad.
