Infliximab downregulates MAP

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kiny

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http://www.ncbi.nlm.nih.gov/pubmed/22398081

"Macrophages infected with MAP were collected and
processed as published.8 Interestingly, we observed a significant
decrease in the survival of MAP when macrophages were
exposed to infliximab (Fig. 2), suggesting that the suppression
of TNF-α was detrimental to the intracellular survival of MAP.
We found no difference in the survival of MAP between different
times of infliximab exposure to macrophages prior to the
infection."
 
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