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Sorry I wasn't very clear in my question. The study I was talking about is the SSI taking place in Canada for moderate to severe Crohn's patients. (hence why i posted this reply on this thread) Should my son take the chance with volunteering for this study or continue with the LDN which he has been on for only a short time. He is doing well on it but we are still not sure that it is the reason for him doing better.  He had 1 [wiki2="Flare"]flare[/wiki2] but that could be because he stopped the LDN for 5 days because of a rash he has developed he has been under a naturopaths care as well so it is hard to know what is working and what is not