Is Crohn's Disease due to immunodeficiency or autoimmune

[Dekar]

"there is an increasing body of evidence in favor of the hypothesis that Crohn's disease results from an impaired innate immunity.[46] The immunodeficiency, which has been shown to be due to (at least in part) impaired cytokine secretion by macrophages, is thought to lead to a sustained microbial-induced inflammatory response, particularly in the colon where the bacterial load is especially high."

 

[Crohns08]

Could you post the source of this quote?

 

[EthanPSU]

Honestly...I just read that and didnt understand a word you said....

 

[fateful_one]

sounds plausible, but i am actually more intrigued by the hygiene hypothesis.

http://en.wikipedia.org/wiki/Hygiene_hypothesis