I started on Humira about 6 weeks ago. I was also really worried about the side effects, but I spoke with my wife's uncle who is an internist and also worked for the CDC. He really helped put my fears to rest. He basically told me that, although there are possible side effects, the risks definitely outweigh the rewards. He also told me that, even if there is the slightest most unlikely to happen side effect, they still must list it as a possible side effect. So far, I've gone through the loading dose and the second dose of two injections and am due for my next one this Friday. So far, so good. I haven't noticed any side effects so far.