Studies over the last 10 years or so suggest there may be a continuum between IBS and IBD, with some IBS patients having "low grade inflammation".
I am a case where I've been diagnosed with IBS due to negative results for e.g. calprotectin and other conventional markers for inflammation, yet, because I experience numerous extra-intestinal symptoms, it suggests something more is going on.
Pain and motility medications for IBS don't treat any of these extra-intestinal symptoms. If there is "low grade inflammation", this may explain why.
Just wondered if anybody has any relevant experiences on this score. I know there are some trials being done with e.g. mesalamine for IBS (and some that have been done, with mixed success). But what I'd be interested in is personal experiences - e.g. a gastro that actually explored this avenue.
I am a case where I've been diagnosed with IBS due to negative results for e.g. calprotectin and other conventional markers for inflammation, yet, because I experience numerous extra-intestinal symptoms, it suggests something more is going on.
Pain and motility medications for IBS don't treat any of these extra-intestinal symptoms. If there is "low grade inflammation", this may explain why.
Just wondered if anybody has any relevant experiences on this score. I know there are some trials being done with e.g. mesalamine for IBS (and some that have been done, with mixed success). But what I'd be interested in is personal experiences - e.g. a gastro that actually explored this avenue.