N-Acetylglucosamine

[nogutsnoglory]

I have seen some studies that suggest this supplement can help repair the gut lining. Anyone take this? I think I will add this to my regiment.

 

[kiny]

I have it but don't use, NAG is usually not sold in pure form (even if it is, I don't know how stable it would be), it usually tends to be a form of shellfish with NAG in it. Safety profile of NAG is also not established, but since it's non-essential, there haven't been many safety tests. (studies use pure NAG, something you won't easily find without getting it made)

NAG is often confused with Glucosamine sulfate btw.

 

[nogutsnoglory]

I couldn't even find it at whole foods today. Just saw regular glucosamine.

 

[mnsun]

I know there is a Source Naturals "n-a-g" product and a Thorne Research "Perma-Clear"--this one, a complex with glutamine, b. coagulans, s. boullardi, quercetin and ginger.

Haven't tried them.

 

[Livilou]

My son takes Jarrow Formulas N-A-G 750..he tolerates it well, just not too sure if it's helping much with CD. My daughter uses a powder form of NAG made by Ultimate Glucosamine ( they have a website). I give her 2 scoops/day. Not much else is added to the powder, although ingredients list N-Acetyl-D Glucosamine(shrimp). Beware if you are allergic to shellfish! Also, powder is a bit pricey...about $32 for 2.1 oz of powder.

 

[mnsun]

I now take 1-2 caps of Jarrow 750mg NAGlucosamine daily, about a half hour before consuming caffeine, to great effect. I definitely notice this stuff gives me a shield against any harmful effects of caffeine/coffee.

I'm not particularly versed on just why this helps so much, but I just found a study which seems to have just collected dust after reporting substantial benefit to children taking 3-6 grams daily (some took it rectally, even). I may have to up my dose... I think it has something to do with macrophage function and mucin production.

Check it out: http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2036.2000.00883.x/full

Alimentary Pharmacology & Therapeutics
Volume 14, Issue 12, pages 1567–1579, December 2000
"A pilot study of N-acetyl glucosamine, a nutritional substrate for glycosaminoglycan synthesis, in paediatric chronic inflammatory bowel disease"

S. Salvatore1,
R. Heuschkel1,
S. Tomlin2,
S. E. Davies3,
S. Edwards4,
J. A. Walker-Smith1,
I. French5,
S. H. Murch1

Article first published online: 2 JAN 2002

DOI: 10.1046/j.1365-2036.2000.00883.x

 

[nogutsnoglory]

Do you feel it is helping with your crohns? When you say effects of coffee do you mean heartburn or effects of energy levels?

 

[kel]

I'm assuming the diuretic effects from caffeine.

 

[mnsun]

Coffee, probably due to localized inflammation immediately outside of my stomach, can send me to the restroom in minutes after consumption--not all the time but A LOT of the time--if I don't take this stuff as a buffer of sorts. It's really the only food that does that to me so consistently.

 

[nogutsnoglory]

You find this supplement relieves of the need to goto the bathroom from coffee? That's interesting not sure why it would.