Purple wrinkles under the eyes

[Stuffette]

purple wrinkles under the eyes

I have been noticing dark purple wrinkles under my lower eyelashes. It looks like someone drew under my eyes with a purple eyeliner. At first I thought that I was just getting wrinkles and I should just accept the fact that I am getting older. The problem is that I am only 33 and I don't think I should have such dark, deep wrinkles.

I am taking Asacol. Has anyone else noticed this as a side effect? I also have been losing my hair. I have such thick hair that it doesn't bother me much though.

 

[Jeff D.]

Are they wrinkle or rings because dark rings can be caused by not having enough sleep.

Good luck, never took Asacol but thats the only thing I know.

 

[Stuffette]

wrinkles

They are wrinkles. They are different from the usually bags I get from not getting enought sleep. They are right at the eyelashes. I get lots of sleep even though I don't ever feel like it. I get about 7 to 8 hours a night.

They are probably just wrinkles from too much fun in my twenties and too much sun in my teens.

 

[old hat]

Mesalamine causes hair loss in a small percentage of patients. It seems to be a dose dependent side effect.

http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=8553032&dopt=Abstract

[Diffuse alopecia as side effect of mesalazine therapy in Crohn's disease]

[Article in German]

Netzer P.

Abteilung für Gastroenterologie, Klinik C für Innere Medizin, Kantonsspital St. Gallen.

Within the scope of the participation at the VI. European Crohn's Disease Study we observed under therapy with 4 g/day Mesalazine (Pentasa) a strong diffuse hair loss on two female patients which disappeared again after discontinuation of therapy. A repeated positive exposure in both patients confirmed the causality. One patient had thereafter a recurrence of Crohn's disease so she was given a reduced dose of Mesalazine (2 g/d). The hair loss began again but on an acceptable level for the patient. Thus, it looks like a dose-dependent side-effect as it is known in the medical literature. These are so far the first two cases of hair loss in connection with Pentasa recorded by the Swiss Drug Monitoring Center. In the medical literature there are reports about this side-effect from all producers known in Switzerland (Asacol, Pentasa, Salofalk), which suggests a Mesalazine specific side-effect. Since recently higher doses of Mesalazine (2-4 g/d) are used in Crohn's disease, a reversible and probably dose-dependent hair loss must be expected in 1-2% of these patients.