Some Interesting Results

[Raleigh]

Hi Everyone,

I've been waiting for my biopsy results since my colonoscopy on May 17th. My doctor suspects Crohn's or UC because I have a multitude of IBD symptoms, and my colonoscopy showed some rectal inflammation.

In the meantime, while waiting on the biopsy results, some blood work has come back abnormal. I was hoping you guys could let me know if the results that I had are common with Crohn's patients, or if you have had similar results. So here they are:

1.) Iron Deficiency
I know that this is very common with IBD. It has been a chronic problem for me, and I had to get an iron infusion last year.

2.) Vitamin D Deficiency
This has also been a chronic problem for me.

3.) High IgE
Normal Range: <114 Mine: 335

4.) Low PTH (Parathyroid Hormone)
I'm not sure about the normal range, but he said mine was very low at 5.

That is all I have right now. Any insights or experiences would be greatly appreciated! Thanks so much.

Brian

 

[EthanPSU]

For me with those four...

Iron Deficiency....

I had a huge Iron deficiency when I was first diagnosed, and like you said it is a big problems with crohns and IBD. I took a series of Iron Tablets to get this under control

Vitamin D Deficiency...

I have never really had any experience of this...I'm not sure if it's related to the disease or the person

High IgE...

Honestly...haha...I have no idea what IgE means or is...

Low PTH...

Not sure about that one either..

 

[Raleigh]

I'm surprised you could handle the iron tablets. They tend to make people with healthy bowels nauseous, never mind people with Crohn's. I had to get an infusion a year ago. It's not a fun experience. Now my iron is low again, which means it's back to the hematologist for me.

 

[nikimazur]

Ige is another inflammatory marker? Parathyroid is a hormone, which is crucial in calcium storage and release into the blood stream. In some autoimmune disorders ie. Crohns, this hormone is lowered, which can play havoc with calcium levels. It is often found in the intestines, which may play a role in which is lowered in autoimmune disorders of the bowl. Wiki does a good job of explaining both in Laymans terms, but just googling either should help. With the low parathyroid levels, your physician should also test blood calcium levels as well as vitamin d again because these both are dependent on the parathyroid hormone.

Hope this helps!

 

[Raleigh]

Strangely enough, I'm pretty sure my calcium levels are ok. It is in my TPN, so I get it every day. I wonder if this has any effect on vitamin D, since it is related to calcium.

I'm just wondering if the low PTH is common among Crohn's sufferers, or if it's just me. I found some medical literature that found that PTH is lower in pediatric Crohn's patients, but it doesn't seem too common on this forum.

IgE is released during allergic reactions. I've also found medical literature linking IgE to Crohn's, but again, it doesn't seem very common with members of this forum.

 

[nikimazur]

My pth levels were lower, and had numerous tests to rule out any other cause besides crohns. Though your calcium levels are not effected yet, it would be a decent idea to monitor them to make sure there is no fluctuation. Low pth or hypoparathyroidism canalso contribute to low vitamin d levels too.

IgE testing isn't typically part of a Crohns bloodwork up, nor is PTH, so it may be way many of those on the forum haven't commented about it. It also is not a great indicated of crohns or inflammation, but has some ties.

Other markers such as Iga or anca/asca antibodies are more common and used more so through out the forum as well

 

[toml99]

Low iron levels and low Vitamin D levels are common with Crohn's, due to the interference in absorbing them in your small intenstine. Low Vitamin B12 levels are also common. These are pointers to CD, but can also be caused by other factors. Hope you get your diagnosis soon.