I've watched my two older brothers suffer from Chrohn's all their life. I thought I got lucky and escaped their fate. I'm a healthy, marathon runner in my early 50's. On 12-30-2010, after ignoring my symptoms for weeks (thought it was a stomach bug I'd get over), my friend talked me into going to a dr. I'd been so healthy, I didn't even have a regular doctor, so went to a clinic. She did a cat scan, thinking I'd be having an appendectomy that evening. Instead it turned out to be suspected Chrohn's. I was sent to UW Medical Center for 2nd opinion. They confirmed it. I started on a small (25mg) dose of 6mp on 4-22-2011, and have titrated up to 75mg by May 27th. I'm an intermediate metabolizer, so I'm "iffy" if I'll be able to succeed in taking it. I've had a few, discrete, weird events, with general fatigue and a little bit of nausea, but think I'm managing. We shall see! Would be nice if the abdominal pain from this initial flare would fully go away, but trying to be patient waiting.