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Depends

When Ds took shots of mtx he was sick for 6 days then it was shot day again

When he takes mtx pills at 25 mg again he is sick for 4-5 days

At 20 mg pills he splits the dose 12 hours apart

Takes 2 mg of folic acid (folate )

Then is nauseous starting 24 hours afterwards

Not sure how long that lasts since he just deals with it now and pushes through

I can ask later


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