I'm a program coordinator at a literacy non-profit, the pay isn't great but it's worth it for the flexibility; a lot of the time I can work from home if I need to, come home for lunch, and my hours are only 8-2:30 Tue-Fri with some night-time programs every few weeks or so. It's rewarding work. On the side, I do graphic design and web design, which I'm hoping to turn into a full-time gig from home in the next couple of years.
Before this job, right after I graduated college, I was a producer at a broadcast news channel in Nashville, working overnight for the morning show (10pm-8am) 5 days a week. That only lasted a year, and I'm surprised I made it that long! ZERO flexibility there and a lot of really silly scripts written for "serious" news anchors. 