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This seems to be the most unsafe drug ever to get an approval for the treatment of CD. I wouldn’t consider using jak inhibitors unless I really had no other choice.

I think the current map vaccine trial with Crohn’s patients will prove the vaccine is ineffective in treating Crohn’s disease. I don’t expect any further trials with the vaccine after that. Rhb-104 antibiotic cocktail that was supposed to be “anti-map” also resulted in more or less the same...

From CMV’s FB Group: “Many members of this group have been with us for 7+ years through all of the fundraising, setbacks, fears, and tears, and sadly some members are no longer with us. For those that are, we are now only just over a month away from the end of the phase 1b and six months from...

https://www.utahbusiness.com/sorriso-pharmaceuticals-is-creating-the-first-orally-delivered-anti-inflammatory-drug-for-patients-with-ibd/

Open AccessObituary Hermon-Taylor: M. paratuberculosis and Crohn’s Disease—The Book of Revelation According to John by Coad Thomas Dow McPherson Eye Research Institute, University of Wisconsin, 9431 WIMR, 1111 Highland Avenue, Madison, WI 53705, USA Pathogens 2021, 10(11), 1469...

MAP Specialists MAP Doctors and Research Centers Around the Globe E-mail Human Paratubetculosis Foundation. They will most likely help. Also use various Crohn’s Map Facebook groups.

E What about MRI without contrast? Don’t they do that for him?

https://finance.yahoo.com/news/rapid-improvement-remission-patients-refractory-231900721.html

"Trial update and a call for volunteers!"

You’re welcome.

The update posted here by @Delta_hippo was provided by that patient: Crohn’s Map Vaccine has a Facebook support group. There hasn’t been any updates other than that posted by @Delta_hippo above.

https://www.fda.gov/drugs/drug-safety-and-availability/fda-requires-warnings-about-increased-risk-serious-heart-related-events-cancer-blood-clots-and-death

Home-made, plain coffee.

As for interesting research to follow, in addition to fimh blockers and phages, there are also SSI and MAP vaccines, rhb-104, and stem cell therapies.

Marketing.

https://www.prnewswire.com/news-releases/enterome-highlights-microbiome-publication-describing-sibofimlocs-novel-mechanism-of-action-for-the-treatment-of-crohns-disease-301378453.html

What about chocolate? How does your son do with coffee and chocolate? You may want to research home made bone broth, for your son’s health. It reduces intestinal inflammation significantly.

I hear you, chocolate causes tooth pain for me. For this, I have found the ratio of cocoa to be important. Increased cocoa ratio (say, 90% cocoa compared to 70%) in the chocolate means there is less sugar in it, which translates as less tooth pain for me.

Black tea? When you stopped drinking coffee cold turkey, have you experienced a betterment in your digestive system?