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FYI for what it's worth. Old Mike http://www.upmc.com/media/NewsReleases/2016/Pages/duerr-crohnsmicrobiome-gastro.aspx

Quite interesting. About time. This was also know at least 10 years ago. Old Mike http://www.mountsinai.org/about-us/newsroom/press-releases/research-collaboration-identifies-serum-biomarkers-that-predict-pre-clinical-ibd-development-and-complications

I just happened to find this report by accident. Seems crohn's remissions were involved with itraconazole treatment. Old Mike http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2036.2010.04444.x/full

This sort of the opposite,of the thread subject. Extra sodium ions in the skin enhances macrophage killing. So in might be interesting to know if sodium ions are also stored in the small intestine tissue. I know sodium ion is also stored extracellular in other tissues such as muscle and possibly...

Not really sure why they moved my post out of the research area, its taken me a little while but I was getting to crohn's disease. I have also ran a search on the whole forum and do not come up with Alequel. Old Mike Looks like this might somewhat contradict theory,there might be some hope...

Here is some more info. Seems that it can create a more pro inflammatory immune system in days, I wonder about a lifetime. Old Mike http://www.medicalnewstoday.com/articles/257319.php http://www.scientificamerican.com/article/salt-linked-to-autoimmune-diseases/ more on high salt diet and...

Based on my history. UC 1980,quit smoking in 1977. Prior history none. Now back in 1971 Nov-Dec, a good case of Korean craps,resulting in D for about 2 weeks. One day with the burning D, I felt something tear and a burning sensation for about 3 days, went away and did not think about it...

What else you getting with FMT,just a FYI. Old Mike http://www.ncbi.nlm.nih.gov/pubmed/27025251

Here we go, if Curcumin acts the same way on MAP as TB we might have something,increases autophagy and apoptosis. Old Mike http://medicalxpress.com/news/2016-03-curcumin-drug-resistant-tuberculosis.html Abstract Background and objective With the worldwide emergence of highly...

I researched this back in 2013, it has possibilities for the oral tolerance mechanism. I also believe there is a difference in the bacteria trapped in the nose, vs what you swallow. Old Mike http://abcnews.go.com/blogs/health/2013/04/30/professor-asks-if-eating-boogers-boosts-immunity/ here...

This has been know for years on alternative sites, I tried it a few years back, seems to have made me worse,when taking. Acetic acid rectally will of course induce a mouse colitis, but orally don't believe it will make it to the colon. That being said with IBD, who knows. The other interesting...

Irish: Sure anything is possible with this type of work. I have been a big believer the MAP connection, for years. For me this study, invokes a somewhat different research path, as to what is going on with crohn's and the pre crohn's ulcers. this might be a clue...

All good points JMC, I will just leave it there until myself or someone else, comes up with more info on these pre crohn's ulcers. Read the links I posted on these ulcers above may provide more insight. I also suspect that this might be somewhat difficult to determine, since you don't know your...

Also of interest is the strain that likes to grow at 5 degrees C, that might suggest a strain that has adapted to refrigeration. But the real point of interest from the paper is that MAP may be a an after the fact bystander. I wonder if the MAP positive people had worse symptoms, or they were...

JMC: Interesting paper,now perhaps raises more questions. Only finding 29% MAP in the N=22 CD people. What worse they raise the question of when is the MAP acquired, since they found no MAP in the intestinal aphthous ulcer people. They also found MAP in a few UC people. I guess the GI community...

Early onset crohn's seem to be dysbiotic from the get go. I could guess that the symptoms don't get bad enough,to realize there is a gut problem until the dysbiosis reaches a certain tipping point. Old Mike http://www.ncbi.nlm.nih.gov/pubmed/24629344

Since I have been researching IBD for about the last 36 years I am sort of running out of stuff to look at. Whether MAP is causal or a bystander in Crohn's don't know,but here is a somewhat different research path to look at. Will actually tie in with my iron thread. One aspect of nutritional...

Hi David: Not much out there on the subject. Here is something. Old Mike http://pediatrics.aappublications.org/content/84/5/851?sso=1&sso_redirect_count=1&nfstatus=401&nftoken=00000000-0000-0000-0000-000000000000&nfstatusdescription=ERROR%3a+No+local+token here is something on iron anemia and...

As long as I am talking about iron. Might as well talk about how to absorb more, not let it get to the colon/distal small intestine, and if you absorb more then also help with anemia. phyate and ascorbic acid/orange juice Drink juice with high phyate meals...

Here is something search the doc for gallium. Seems that it binds with siderophores for iron and the bacteria cannot use it. Old Mike Will add more to this post when I find it. http://www.tdx.cat/bitstream/handle/10803/129292/ggo1de1.pdf?sequence=1 willincrease virulence factors, I have to...