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I know that is how they do it but is it the best way. There is going to be oxygen in the saline, unless air is removed. 50% die in 4-5 minutes, so depending on how long people mess with this you can have variable amounts of live bacteria. Which brings up the question, do you even need a whole...

Acid suppression not sure might be a bad idea, let the body sort out what it wants to kill. As far as what you are doing limit the stools exposure to air as much as possible, it may kill the strict anaerobes, and saline may also kill, do to osmotic rupture of cells. Mashing the stool may not...

Here is something on oral tolerance, which was a big theory for IBD years ago. Since they used a nasoduodenal tube the stool is released into the first part of the small intestine so basically the whole small intestine is exposed to the bacteria and any antigens. The immune sampling for oral...

The point I believe is that as long as you are making excess peroxides the VDR is inhibited. New cells would also exhibit the inhibition in the presence of excess peroxides. So yes,after reduction of peroxides and or remission the VDR would be restored. Old Mike

I may have posted this before, but what does anyone make of this. The controls were given their own poo for the transplant, and remission took place is some. A wild guess might be oral tolerance induction, or placebo effect. Old Mike Findings From a Randomized Controlled Trial of Fecal...

Here is an interesting paper on what goes on with FMT and Sepsis,case study. Lots of good info on before and after gut bugs. I might suspect much of the same happens with IBD and FMT. Old Mike http://www.omicsgroup.com/conferences/ACS/conference/pdfs/16568-Speaker-Pdf-T.pdf

Thanks Mark interesting. I have posted lots on MAP, not here so much but on healingwell. That is where I normally hang out,since I have UC. There are many here who know more about crohns than I do, but I have been researching the literature on IBD since 1980,now if I could only remember the...

Here perhaps is what is actually going on. Peroxides irreversibly inhibit the VDR. So if the VDR is inhibited you can take all the Vitamin D you want, and have high serum vitamin D level but, its action will be inhibited due to lack of VDR. http://www.jbc.org/content/277/15/13294.full.pdf From...

IC:There is a lot more going on with Crohn's, much perhaps is down stream of causative events, so makes it difficult for the doc's and us to figure it all out. Here is something else going on,defective oxidative bursts. I am UC centric but keep tabs as to what is going on with crohn's. Old Mike...

You may find this of interest. Old Mike http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378665/ history fluorescents started around 1904 http://en.wikipedia.org/wiki/Fluorescent_lamp here is a short history of IBD http://www.wjgnet.com/1007-9327/7/175.asp If you are really interested here is an...

I have been trying to figure this stuff out for about a year. Interesting that plant-type sphingolipids called sphingadienes cannot be metabolized to S1P and instead enhance the metabolism of S1P by increasing SPL levels. Vegetarians get UC but perhaps not that many. Old Mike...

This just popped up on pubmed. No seasonality for UC, but yes for crohns, worse in summer. Old Mike http://www.ncbi.nlm.nih.gov/pubmed/25976931

Well here is something else going on. Oxidized food hitting the stomach. Grilled meat going to be much worse than stew. Old Mike http://www.fasebj.org/content/22/1/41.long

Some might find this of interest if you have crohns. Where as arginine makes my UC worse, as they note in the paper. Old Mike http://jn.nutrition.org/content/138/12/2481.full

I believe the medium rare is the problem. If rare or medium rare the immune system will see the steak as a foreign protein. If cooked well the protein will be denatured and not look foreign to the immune system, or perhaps not even look like a protein at all. Old Mike

This ties in with my research on taurine, which will protect macrophages from ROS but it will also protect the intercellular bacteria from being killed. Arginine will make more NO from inos, is that what crohns people need. I have UC arginine supplements make me worse. A question might be...

FYI: Something new just popped up, difficult read. Old Mike http://gut.bmj.com/content/early/2015/04/16/gutjnl-2015-309333.full.pdf+html

If you have crohns, cloves might be counter productive. Since the mucus layer is thickened in dimension good for UC, but in crohns the mucus viscosity is too thick. Don't believe the study talked about viscosity. At any rate with crohns the mucus stays in the crypts and does not expand to flush...

Thanks WB: I am always looking for ways to increase the mucus barrier for UC. Of course this study used a real low dose in the mice only 13 ugm/ml of drinking water. Higher does of essential oils tend to kill bacteria in the gut. Old Mike

Ok here is something brand new, and not good on FMT, sad. At least for UC. Cannot get the paper but can get supplement info which pretty much tells the whole story. I cant help but wonder if the donor stool prep kills off important anaerobes. These 3 people got up to 30 rounds of FMT, but all...