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Farmwife: Sorry to here about your daughter. Growing up on a farm is associated to be protective for IBD,unstearlized water in China also associated with protection. Why just your daughter might have it don't know. But even identical twins have different microbiomes,depending on different...

Sorry to here this mlp, been trying to figure IBD out for the past 34 years, not yet. I have two young grandchildren, I am sacred to death and driven to solve it. You don't happen to live near any dairy farms, or rivers that drain farm land, do you. I try and go out of the box on theories every...

Lot of smart people here,thought I would put this up for discussion,just in case there is a possibility that this mechanism is involved somehow in IBD. This is an old study,but now have to wonder if we are eating/supplementing too many antioxidants. Something defective in iNOS pathway too much...

Perhaps big pharma knows exactly what they are doing with biologics,if this testing is meaningful. Killing MAP. One way or the other. Don't know how this one slipped out it is a 2010 poster. Old Mike http://www.pulsus.com/cddw2010/abs/114.htm Believe I have also read that specifically Remicade...

JCM I have no idea. But just ran across this, cigarettes are loaded with MAP. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC228569/pdf/332757.pdf Old Mike

I am sort of on the same trail,where most of the IBD meds enhance the immune response against MAP,or inhibit growth. If fact there is a pretty good story that since about 1942 the GI medical community has unknowingly been modulating MAP infection with all the meds that work on IBD. Anyhow this...

Thought I would add some other info to this thread. We all know SCD and Paleo diets, helps some people,and exclusion of wheat helps some. Yet normal allergy testing may not show much. Ok where am I going with this. Zyrtec is a histamine 1 receptor blocker,other newer antihistamines may...

This was posted on the site in the past. But it is interesting that they are calling the whole gi medical community since 1942,basically stupid. Old Mike http://www.sciencedirect.com/science/article/pii/S1201971214014349

Interesting 20% of humans lack the gene to make fucose. Old Mike http://medicalxpress.com/news/2014-10-gut-bacteria-host-illness.html

They finally published the complete study online. Just click on pdf to the right. Old Mike http://journals.lww.com/ibdjournal/pages/articleviewer.aspx?year=9000&issue=00000&article=99372&type=abstract

Xiaofa: There is no doubt in my mind that artificial sweeteners disrupt gut bacteria, so therefore they would seem to be a risk factor for IBD. Yet multiple millions ingest sweeteners and do not have IBD. Of course there are multiple millions that have IBS which might be a mild form of gut...

Xiaofa:Just an aside. I quite smoking 1977 UC 1980. My wife quit smoking at the same time, no IBD. She also drinks about a 12 pack of diet pepsi a week,no IBD. There is of course something else going on as risk factors,such as genetics,MAP infections. Also this was off my radar, MAP is in...

Xiaofa: Here you go new study,artifical sweeteners really messing with our gut bacteria,they even tested saccharin so you might be thrilled. I cant get the whole paper but sure someone can. Also tested with humans. I don't eat any but still have UC,never the less quite interesting. Old Mike...

Lara: Here you go here is one on goat herders in india. You can search here for MAP or google for MAP and crohn's you will find much info. What kind of animals do you work with, are any sick. You can also search crohns clusters. Old Mike http://www.ncbi.nlm.nih.gov/pubmed/21703899 I urgently...

Now this is scary,gets into fruits and veggies,never saw this before. This is about mycobacteria in general but if you read there is also a specific study on MAP. The MAP experiment on page 138 but the rest is also interesting. Old Mike Link

I know this is an old thread but been looking into this myself now. Might apply more to Crohns,but have not done enough research yet to know. Interesting theory/results. Just suppose that in addition to gut leaks/mucus breaches we are low on igA,makes a lot of sense. igA is attached to and...

Well here is a new one as of this am. I would have loved to see that the mice did not recover at all. What bothers me about most wild type DSS induced inflammation is that in most cases the mice recover,while we don't. Old Mike http://www.ncbi.nlm.nih.gov/pubmed/25144571

Might as well give it a shot, 700 different species. Will be interested to see if you get any improvement. By the way the baby also gets flora when passing through the birth canal. Old Mike...

I don't know. But it seems that when the disease is active the small intestine is more leaky,which allows more food antigens to present to the immune system. That being said elemental diets can put crohn's into remission. So working backwards if these food antigens were not there in the first...

You might find this paper very interesting from Japan,also has UC data. Read the food table if nothing else. Old Mike http://download.springer.com/static/pdf/163/art%253A10.1007%252Fs00535-014-0981-8.pdf?auth66=1407673558_8f09d2be0153728eb9e23f81a7016e2d&ext=.pdf