Well my levels are showing liver toxicity from the 6MP, so my doc lowered the dosage and threw in a new med, Allopurinol, a gout pill. It will help with my kidney stones too. Talked to the doc and wanted to know how concerned she was about 6MP and future fertility, and she replied to my disappointment, "You're already at a disadvantage to concieve with chronic inflammation". Tough week, but chugging on!