Biliruben levels on methotrexate

[Willowcat05]

Hi just been to see jacks gi his biliruben levels have elivated to 41 he asked if I had noticed if he had been jaundice all other bloods have came back normal gi thinks it could be his gallblader he has to have more bloods checked has anyone had these problems on methotrexate? If its not one thing its another with this disease .

 

[Jmrogers4]

Doing some research. One question does he take folic acid along with the mtx?

 

[Willowcat05]

Hi jmrogers4,

He is on 5mg folic acid takes it day after injection. Thanks for deleting duplicate thread didnt know how to do it.

 

[my little penguin]

When DS had to take Mtx , he was placed on folic acid everyday but shot day so six days a week .
Not sure if that helps .

 

[Jmrogers4]

Just was reading an article about folate levels and mtx and liver although it was for RA. Here is the article. I have not had a chance to read in depth
http://rheumatology.oxfordjournals.org/content/42/10/1266.full
I will do some more research and see what I can find once I get caught up here at work.

 

[Willowcat05]

Thanks article was interesting wondering if he should be taking folic acid everyday but injection day maybe thats whats wrong not getting enough foliate?

 

[CrohnsKidMom]

My son is on MTX, but has not had this issue. FYI, he takes 1 mg folic acid daily, except for injection day.

 

[Sascot]

No idea sorry. Hope it ends up being nothing to worry about

 

[Maya142]

My daughter also used to take folic acid (1mg) every day but injection day. Not sure if that would make a difference though?

 

[DanceMom]

Why not take folic acid on injection day? We were never told to skip that day. Hoping I haven't been screwing things up!!

 

[Maya142]

It has to do with the mechanism of mtx. We've been told it doesn't really matter whether you take it on injection day or not, it seems like every rheumatologist/GI has their own way of doing it.