Definitive diagnosis of enterhopathies such as celiac sprue Crohn's disease, and general malabsorptive or diarrheal disorders is often possible only with a small bowel biopsy. While duodenal or occasionally jejunal biopsy is possible endoscopically, the diagnosis may require a more specific site. Laparoscopy offers the potential for full-thickness, specifically directed biopsy." It also affords the option of visualization of the serosal surface of the bowel, which may aid in confirming diagnoses, especially in cases of suspected Crohn's disease.