Effects of anthocyanin-rich tea "Sunrouge" on dextran sodium sulfate-induced colitis

[kiny]

they induced colitis in mice with dextran sodium sulfate, they administered green tea via a stomach tube for 3 weeks, one type of tea worsened the collitis, the other partially improved it, it was down to the type of tea, Yabukita is high in green tea polyphenols which seems to worsen collitis they think and they think the reason Sunrouge improved the mice is because it's high in anthocyanins. Anthocyanins is the stuff in blueberries and rasberries, it had nothing to do with innate properties of tea, the green tea polyphenols worsened the collitis, it had to do with the make-up of the tea extracts.

The idea that green tea is good for crohn stems from a study from 2005 I think, where they saw improvements in mice, but unlike this team that has shown twice now that green tea polyphenols did not help and could even worsen colitis in high dosis, they did not take into account what other stuff was in the tea and they also did not use a control tea.

Effects of anthocyanin-rich tea "Sunrouge" on dextran sodium sulfate-induced colitis in mice.
Akiyama S, Nesumi A, Maeda-Yamamoto M, Uehara M, Murakami A.
Source

Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Japan.
Abstract

Sunrouge, an anthocyanin-rich tea, has similar levels of catechins as "Yabukita," the most popular green tea cultivar consumed in Japan. Green tea polyphenols (GTPs) have attracted interest due to their potent antioxidative activities combined with a lack of side effects in humans at normal consumption levels. However, we previously reported that high doses (0.5 and 1%) of dietary GTPs can result in deterioration of colitis and failed to prevent colon carcinogenesis in inflamed colons. In the present study, we determined the inhibitory effects of Sunrouge on colitis in dextran sodium sulfate (DSS)-treated and untreated control mice. Five-week-old female ICR mice were administered a single dose of Yabukita or Sunrouge (extracts in 1 mL distilled water) via a stomach tube for 3 weeks. After 1 week of treatment, the mice were divided into four groups (two Yabukita and two Sunrouge groups) and given drinking water with or without 3% DSS for 2 weeks, then they were euthanized. Those treated with DSS developed watery diarrhea and bloody stools, and showed body weight loss, spleen hypertrophy, and shortening of the colon, as well as deteriorations in survival rate, liver function, colon mucosal interleukin-1β level and expression of phase II detoxification enzyme mRNA. Sunrouge improved these DSS-induced symptoms, at least in part, whereas Yabukita showed either no effect or adverse effects in regard to some those parameters. It is suggested that the differences between Yabukita and Sunrouge on DSS-induced colitis might be due to the high levels of anthocyanins found in Sunrouge tea.

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