GI appointment update

[FrozenGirl]

So today I saw my GI again. 4 weeks ago I had a cope that showed since stopping Imuran I was flaring (had to stop due to chronically low WBC count even on very low doses) I was put on pred (20mg) which helped but no remission.

He agreed we needed to change something. He gave me 4 options.
1. Add methotrexate to Remicade
2. Stelera
3. Entivyo
4. Surgery

I chose Remicade with methotrexate 12.5mg. I wasn't ready to switch biologics yet since it was working well with Imuran and he has never had a patient on Entivyo (it is only going to be approved here starting next week). We both agreed I wasn't at the surgery point yet.

I did my first injection about an hour ago and it went really well. Here's hoping.

Anyone have experiences on when it will start to help? Side effects? ( I will be cross posting in the methotrexate forum but I figured more people would see it here)

 

[SarahBear]

Sorry to hear you're flaring.

I'm not sure exactly how long it took for me to feel the effects of methotrexate, as I was on high doses of Prednisone, so things are a little foggy. However, I didn't have any side effects I would attribute to the MTX.

How are you feeling now?

 

[my little penguin]

Mtx takes about 8 weeks to be effective
But DS saw side effects after a week
High dose folate eliminated those
DS take 12.5 mg orally ( not injection ) with his humira
He also takes 1mg of folate twice a day
Otherwise he gets fatigue and mouth ulcers with Mtx.

Good luck

 

[FrozenGirl]

8 weeks, ugh. Feeling pretty gross since I am 4 days away from my Remi. Was dizzy yesterday but other than that okay. No mouth ulcers. Hoping it will stay that way. My GI said of you are going to get them most people get them in the first week. I am hoping my next methotrexate shot I can taper a bit off pred.