Had to stop Humira

[Pam48]

I took the 4 load dose and had a small reaction at the injection site. Two weeks later I had to take two and at both sites I had blistering skin for about 4 inches. That was a little over two weeks ago. I might have scars.

I was really hoping that this would help.

I know they are creating new stuff all of the time. I've had bad reactions to remacade, 6mp and now this. Not much left to try.

 

[MikeinBklyn]

Your doc should look into alternatives, maybe Cimzia? or Stellara?

I am sorry to hear about your situation and wish you the best of luck and good health.

 

[Scaryman]

I took the 4 load dose and had a small reaction at the injection site. Two weeks later I had to take two and at both sites I had blistering skin for about 4 inches. That was a little over two weeks ago. I might have scars.

I was really hoping that this would help.

I know they are creating new stuff all of the time. I've had bad reactions to remacade, 6mp and now this. Not much left to try.

I'd be interested in hearing what the doctor had to say caused that reaction if any, was it antibodies?

 

[Pam48]

he didn't say what caused the reaction, but it is listed specifically as a reaction in the warnings.

 

[theOcean]

Simponi is fairly new, but it's labeled as being for people who have had Remicade and Humira fail. Maybe that would work for you?

Maybe talk to your GI about taking antihistamines in the future with your next biologic if you decide to try another one, too! That might help.

You said you had a bad reaction to 6mp, but have you tried other immunomodulators like Imuran or Methotrexate? Being on one of those before starting another biologic might also decrease your likelihood of getting a reaction.

 

[Orchid]

There's also Cimzia, which is currently considered the most tolerable biologic.

 

[Pam48]

The humira was working. I can tell since I've been off it for 4 weeks and the Crohn's symptoms are back.

I took benadryal about 30 minutes prior to taking the shot. My doctor thought the reaction was bad when I saw him 3 days after the shot. It had blistered over a 3-4 inch circle.