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"Abbvie announces new Phase 3 Humira studies for IBD - pediatric UC study and a test of high dose Humira for UC and CD
20th February 2014 16:35
Source: Alert from UpdatesPlus-IBD
Abbvie has announced three new Phase 3 studies of Humira in IBD
The first study is a Phase 3 study evaluating Humira in pediatric UC [NCT02065557]. Data are expected in 2018. Placing this in context, Remicade has a pediatric UC indication; a Simponi study in this cohort has opened although this is a Phase 1
Humira is normally given for IBD as an induction dose of 160mg followed by 80mg two weeks later and then a maintenance dose of 40mg q2w thereafter. Two further studies are are evaluating new treatment regimens in UC [NCT02065622] and CD [NCT02065570]. In both cases a new, higher induction dose is being employed. In the UC study, the higher dose is also being employed through the maintenance period
The studies are expected to complete 2018"
https://www.leaddiscovery.co.uk/edi...-and-a-test-of-high-dose-humira-for-uc-and-cd
20th February 2014 16:35
Source: Alert from UpdatesPlus-IBD
Abbvie has announced three new Phase 3 studies of Humira in IBD
The first study is a Phase 3 study evaluating Humira in pediatric UC [NCT02065557]. Data are expected in 2018. Placing this in context, Remicade has a pediatric UC indication; a Simponi study in this cohort has opened although this is a Phase 1
Humira is normally given for IBD as an induction dose of 160mg followed by 80mg two weeks later and then a maintenance dose of 40mg q2w thereafter. Two further studies are are evaluating new treatment regimens in UC [NCT02065622] and CD [NCT02065570]. In both cases a new, higher induction dose is being employed. In the UC study, the higher dose is also being employed through the maintenance period
The studies are expected to complete 2018"
https://www.leaddiscovery.co.uk/edi...-and-a-test-of-high-dose-humira-for-uc-and-cd