Hi am new to the forum. My husband has crohns and is just trying out new medication. He has been taking Mercaptopurine for a week now and is suffering with some severe side effects including severe abdominal pain, clammyness and loss of appitite, dehydrating gassyness and feeling generally unwell and weak along with being very thirsty. We have contacted the hospital to ask if these symptoms will pass with time but they don't seem to be able to tell us. Has anyone else who has taken this drug had side effects that have cleared after taking this drug for some time if so how long did it take to get over them? He has already given up on the first lot that he was prescribed. Before taking the drugs he felt quite well he is a farmer and usually strong as an ox but currently he is in a bad way. any advise would be welcome thanks