Above normal calprotectin (>200) is generally indicative of crohn's disease inflammation in crohn's disease patients.
But it's not without its flaws. A calprotectin test measures a protein which shows neutrophils have migrated into intestinal tissue. In crohn's disease patients that usually indicates crohn's disease activity, but it could also simply indicate a self-limiting foodborne infection such as campylobacter or salmonella. Calprotectin indicates inflammation, but it doesn't tell you where this inflammation is coming from, the more proximal crohn's disease is, the less accurate it is.
Depending on how long you've been on EN, calprotectin levels should drop. At 4 weeks EN, the majority of crohn's disease patients have calprotectin that is in the normal range indicating remission.
Above normal calprotectin (>200) is generally indicative of crohn's disease inflammation in crohn's disease patients.
But it's not without its flaws. A calprotectin test measures a protein which shows neutrophils have migrated into intestinal tissue. In crohn's disease patients that usually indicates crohn's disease activity, but it could also simply indicate a self-limiting foodborne infection such as campylobacter or salmonella. Calprotectin indicates inflammation, but it doesn't tell you where this inflammation is coming from, the more proximal crohn's disease is, the less accurate it is.
Depending on how long you've been on EN, calprotectin levels should drop. At 4 weeks EN, the majority of crohn's disease patients have calprotectin that is in the normal range indicating remission.
So I saw my Gi guy today and it was easy to get him to order a calprotectin test for me . Just asked.
I also have a primary care doc and I will ask him for crp and esr and probably liver tests to choose for a baseline .
Can you suggest other tests besides these ones that I should try to get ?
I am seriously considering taking rapamycin - can't find much info on it and asking here has yielded no info.
What would you think of an anti-inflammatory like rapamycin , AKA sirolimus ....have any experience with that ?
I find it strange that the side effects of rapamycin seem to be the same as the side effects of Crohn's - Mouth ulcers/sores ..
Cronh's calls it aphthous ulcers . With rapamycin the ulcers are said to be dose limited.
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Found only this one thing from around 2008:
Case Reports
Gut
. 2008 Sep;57(9):1294-6.
doi: 10.1136/gut.2008.157297.
Use of sirolimus (rapamycin) to treat refractory Crohn's disease
" Our patient was treated with sirolimus for 6 months at a dose that maintained serum trough levels of 5 ng/ml. There was marked and sustained improvement in Crohn's disease symptoms with the Harvey-Bradshaw index falling from 13 to 3, in serum markers of inflammation (C-reactive protein fell from 79 to 2) and endoscopic appearance. This is the first reported case of the use of sirolimus to treat Crohn's disease."
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Rampamycin seems to work great in mice 
Below is from 2022
Rapamycin Alleviates 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis through Autophagy Induction and NF- κ B Pathway Inhibition in Mice
Results: Significantly more autophagosomes were observed in rapamycin-treated cells than in controls. Rapamycin remarkably upregulated the expression of ATG16L1 and LC3II, inhibited p65 nucleus translocation and secretion of TNF-α both in vivo and in vitro. The expression of both ATG16L1 and LC3II increased in mild to moderate CD specimens, while no significant difference was noted between severe CD and normal controls. The expression of p65 increased notably in severe CD compared to those in mild to moderate patients.
Conclusions: In LPS-treated HT-29 cells and TNBS-induced colitis, p65 is overexpressed, which results in exaggerated secretion of TNF-α and induce or worsen the inflammation in the bowel. Rapamycin protects against colitis through induction of autophagy, thus inhibiting the activation of NF-κB pathway and secretion of TNF-α.
