Humira Loading Dose: 160/80 vs 80/40?

[Mark in Seattle]

Hello, I'm wondering what loading dose is being prescribed to patients these days. I've read studies that seem to indicate that using a higher loading dose of 160/80 has better clinical results than 80/40. What loading dose has everyone used, and does anyone have an opinion as to effectiveness or side effect levels associated with their particular loading dose?

 

[goldenholds]

A week ago I began a loading dose of 160/80 of Humira. So far it's too soon to comment on the effectiveness as I haven't noticed much improvement or side effects yet.

Interestingly, the nurse said that they only do the loading doses for crohn's patients, not arthritis patients. I'm not sure why, considering the drug was originally used for arthritis.

Goldenholds

 

[IAmTheWalrus]

My loading dose was 160mgs, 4 Humira pens, then 80mgs, 2 pens.

I always thought that was the norm. :/

 

[marjaw]

I took my first dose of Humira today 40mg. Because I moved from Enbrel to Humira, they skipped the loading dose completely.